Isopropylamine → HCID 18373477, compound

HRID 2301511Notes

Reaction equation

HRID 2301511 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH:16]([NH2:19])([CH3:18])[CH3:17].C(N(CC)CC)C>>[CH:16]([NH:19][S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13])([CH3:18])[CH3:17]

Participants

4

Reactant 3

HCID 6363IsopropylamineHCID 8471TriethylamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 18373477HCID 18373477, compoundYield 81%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.5 g, 5.17 mmol), isopropylamine (0.44 m, 5.17 mmol) and triethylamine (1.08 mL, 7.76 mmol) were reacted to form the desired product (1.3 g, 81 %). EI-MS m/z 312 (M-H)−.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-e0a5ea71239243d88d8b74969e843d9f
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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