HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiomorpholine → HCID 18373505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiomorpholine | HCID 67164 | — |
| Reactant | 2,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride | HCID 23447772 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 18373505 | HCID 18373505 | 94% |
Reaction Steps
Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (2.0 g, 6.88mmol), thiomorpholine (710 mg, 6.88 mmol) and triethylamine(l.92mL, 13.76mmnol) were reacted to form the desired product (2.30 g, 94%). 1H NMR (MeOD-d4): δ 7.95 (d, 1H), 7.85(d, 1H), 3.68 (t, 4H), 2.69 (t, 4H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500863B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-4d4bba97a31d4de7b5729fa21a57bfdf |
| Source note | uspto-grants-2002_12 |