Water → HCID 18373486, compound

Participants

Reaction Steps

Following the general hydrolysis procedure outlined in example 15, 1-(azetidin-1-yl)sulfonyl-2,6-dichloro-3-nitrobenzene (510 mg, 1.64mmol), 60% NaH (197 mg, 4.92 mmol) and water (35 μL, 1.97 mmol) were reacted to form the desired product (240 mg, 50%). 1H NMR (MeOD-d4): δ 8.09 (d, 1H), 7.25 (d, 1H), 4.15 (t, 4H), 2.29 (m, 2H).

Provenance & Evidence