HCID 18373486, compound → HCID 18373528, compound

Participants

Reaction Steps

Following the general hydrogenation procedure outlined in example 15, 1-(azetidin-1-yl)sulfonyl-6-chloro-2-hydroxy-3-nitrobenzene (240 mg, 0.82 mmol) was reduced with hydrogen and 10% Pd/C (110 mg) to form the desired product (215 mg, 100%). 1H NMR (MeOD-d4): δ 6.91 (m, 2H), 4.01 (t, 4H), 2.23 (m, 2H).

Provenance & Evidence