HCID 18373485, compound → HCID 18373492, compound

Participants

Reaction Steps

Following the general hydrogenation procedure outlined in example 15, crude N-ethyl-6-chloro-2-hydroxy-3-nitrobenzenesulfonamide (1.34 g) was reduced with hydrogen and 10% Pd/C (400 mg) to form the desired product (800 mg, 82% for two steps). 1H NMR (MeOD-d4): δ 6.85 (d, 1H), 6.78 (d, 1H), 2.85 (q, 2H), 0.95 (t, 3H).

Provenance & Evidence