HCID 53826154, compound → HCID 53930485, compound

HRID 2301624Notes

Reaction equation

HRID 2301624 reaction equation
[CH:1]1([NH:6][S:7]([C:10]2[C:15]([Cl:16])=[CH:14][CH:13]=[C:12]([N+:17]([O-])=O)[C:11]=2[OH:20])(=[O:9])=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.[H][H]>[Pd]>[CH:1]1([NH:6][S:7]([C:10]2[C:15]([Cl:16])=[CH:14][CH:13]=[C:12]([NH2:17])[C:11]=2[OH:20])(=[O:9])=[O:8])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 53826154HCID 53826154, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 53930485HCID 53930485, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Following the general hydrogenation procedure outlined in example 15, (N-cyclopentyl)-6-chloro-2-hydroxy-3-nitrobenzenesulfonamide (0.54 g, 1.7 mmol) was reduced with hydrogen and 10%,Pd/C (0.54 g) to form the desired product (0.45 g, crude). LC-MS m/z 291(M+).

Sources & evidence

ORD record
ord-32ddba358c9140f78add32affe316e94
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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