Triethylamine → HCID 17927806, compound

HRID 2301634Notes

Reaction equation

HRID 2301634 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH:16]([O:19][CH2:20][CH2:21][NH2:22])([CH3:18])[CH3:17].C(N(CC)CC)C>>[CH:16]([O:19][CH2:20][CH2:21][NH:22][S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13])([CH3:18])[CH3:17]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 5338662-(Propan-2-yloxy)ethan-1-amineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 17927806HCID 17927806, compoundYield 89%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.50 g, 5.16mmol), 2-aminoethyl isopropyl ether (0.533 g, 5.16 mmol) and triethylamine (1.42 mL, 10.32 mmol) were reacted to form the desired product (1.63 g, 89%). LC-MS (m/z) 357.0 (M+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-6ea24ca045b0477abbf65940ac221814
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

Loading…