Triethylamine → HCID 17927853, compound

HRID 2301637Notes

Reaction equation

[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH2:16]([O:18][CH2:19][CH2:20][NH2:21])[CH3:17].C(N(CC)CC)C>>[CH2:16]([O:18][CH2:19][CH2:20][NH:21][S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13])[CH3:17]

Participants

Reactant 3

HCID 8471Triethylamine

HCID 66970Ethoxyethylamine

HCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 17927853HCID 17927853, compoundYield 100.5%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.50 g, 5.16 mmol), 2-aminoethyl ethyl ether (0.46 g, 5.16mmol) and triethylamine (1.42 mL, 10.32 mmol) were reacted to form the desired product (1.78 g, 100%). LC-MS (m/z) 345.0 (M+).

Workup

customwere reacted

Sources & evidence

ORD record: ord-7e4fa9e5aadf45c7b2b869123e449ca7
Source dataset: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06500863B1

Reaction notes

Loading…