HCID 17927863, compound → HCID 18373472, compound

HRID 2301647Notes

Reaction equation

HRID 2301647 reaction equation
[Cl:1][C:2]1[C:7]([S:8]([N:11]2[CH2:16][CH2:15][S:14](=[O:18])(=[O:17])[CH2:13][CH2:12]2)(=[O:10])=[O:9])=[C:6]([OH:19])[C:5]([N+:20]([O-])=O)=[CH:4][CH:3]=1.[H][H]>[Pd]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:20])=[C:6]([OH:19])[C:7]=1[S:8]([N:11]1[CH2:16][CH2:15][S:14](=[O:18])(=[O:17])[CH2:13][CH2:12]1)(=[O:10])=[O:9]

Participants

4

Reactant 2

HCID 17927863HCID 17927863, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18373472HCID 18373472, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Following the general hydrogenation procedure outlined in example 15, 6-chloro-1-(1,1 -dioxidothiomorpholinosulfonyl)-2-hydroxy-3-nitrobenzene (220 mg, 0.60 mmol) was reduced with hydrogen and 10% Pd/C (100 mg) to give the desired (186 mg, 92%). 1H NMR (MeOD-d4): δ 6.88 (m, 2H), 3.85 (t, 4H), 3.22 (t, 4H).

Workup

  1. customto give the

Sources & evidence

ORD record
ord-c049c4ab78e74ad796cdf52a9d320cfe
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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