HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sertraline → Sertraline Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sertraline | HCID 68617 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Sertraline Hydrochloride | HCID 63009 | 203.7% |
Reaction Steps
Sertraline base (5.8 gr.) was dissolved in toluene (200 mL). HCl gas was bubbled (about pH 1.5) through the solution. A gel is formed. Filtration and drying at 50° C. for 16 hours gives amorphous sertraline hydrochloride (6.61 gr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500987B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-74085f067c824adaa2cf6b17fa5febc0 |
| Source note | uspto-grants-2002_12 |