Benzyl Bromide → HCID 69978010, compound

HRID 2301996Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][C:10]([O:15][CH3:16])=[CH:11][CH:12]=2)[NH:7][C:6]1=[O:17].[CH2:19](Br)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][C:10]([O:15][CH3:16])=[CH:11][CH:12]=2)[N:7]([CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:6]1=[O:17]

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 12071330HCID 12071330, compound

Product 1

HCID 69978010HCID 69978010, compoundYield 88%

Procedure

The title compound (4.3 g, 88% yield) was prepared using the conditions of Example 124 using (7-methoxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl ester in place of (7-methoxy-2-oxo-1,2-dihydro-quinolin-3-yl)acetic acid methyl ester and benzyl bromide in place of ethyl iodide.

Sources & evidence

ORD record: ord-9be1fd2d75fd401990d100908266fc69
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06429214B1

Reaction notes

Loading…