L-Aspartic Acid → L-Aspartic acid, sodium salt (1:2)

Participants

Reaction Steps

A mixture of 10 g of aspartic acid (0.0751 mole) in 28 ml of water plus 26.6 g of monoamino polyoxyalkylene (Jeffamine M-2070, 0.47 meq NH2/g, 0.0125 mole NH2) was mixed with 4.7 g of 50% NaOH. The salt of sodium aspartate and polyoxyalkylene amine was formed by lyophilization, and a sample of 0.05 g of 4-methoxyphenol was added as an antioxidant. This mixture was heated in a flask in an oil bath at 180° C. for 20.5 hours. Subsamples were taken at 2, 4, 7, and 13.5 hours.

Provenance & Evidence