Pyrazole → HCID 18460356, compound

HRID 2302481Notes

Reaction equation

HRID 2302481 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[N:2]1.Cl[C:7]1[N:8]=[C:9]([NH:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:10]2[CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[S:13][C:11]=2[N:12]=1>>[N:1]1([C:7]2[N:8]=[C:9]([NH:19][CH2:20][C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)[C:10]3[CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[S:13][C:11]=3[N:12]=2)[CH:5]=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 1048PyrazoleHCID 184600152-Chloro-6-nitro-4-benzylamino-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18460356HCID 18460356, compound

Procedure

Following the procedure of Example 97, the reaction of pyrazole with 2-chloro-6-nitro-4-benzylamino-thieno-[2,3-d]-pyrimidine gives 2-(pyrazol-1-yl)-6-nitro-4-benzylamino-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-f1797f84c7b7487a856666752e2ac933
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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