Water → HCID 18618210, compound

HRID 2303290Notes

Reaction equation

HRID 2303290 reaction equation
[C:1](Cl)(=[O:3])[CH3:2].[NH2:5][N:6]1[C:11](=[O:12])[C:10]2[S:13][CH:14]=[C:15]([Br:16])[C:9]=2[N:8]=[CH:7]1.O>O1CCOCC1.N1C=CC=CC=1.CN1CCCC1=O>[C:1]([NH:5][N:6]1[C:11](=[O:12])[C:10]2[S:13][CH:14]=[C:15]([Br:16])[C:9]=2[N:8]=[CH:7]1)(=[O:3])[CH3:2]

Participants

7

Reactant 3

HCID 962WaterHCID 6367Acetyl chlorideHCID 18618206HCID 18618206, compound

Product 1

HCID 18618210HCID 18618210, compound

Reagents, catalysts & solvents 3

HCID 1049PyridineSolventHCID 13387N-methyl-2-pyrrolidoneSolventHCID 312751,4-DioxaneSolvent

Procedure

To a stirred solution of acetyl chloride (0.16 g) in 1,4-dioxan (2 ml) was added a solution of the product from Example 7 (0.5 g) in pyridine (0.16 g) and N-methylpyrrolidinone (0.5 ml) and stirring was continued for 1 hour at room temperature. Water was added and the mixture was filtered to give a solid which was dried to give the title product, m.p. 273° C.

Workup

  1. filtrationthe mixture was filtered
  2. customto give a solid which
  3. customwas dried

Sources & evidence

ORD record
ord-e77aeaa9cbe64820aae66e4af1e79846
Source dataset
uspto-grants-2002_08
Patent number
US06432964B1

Reaction notes

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