HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → Methyl 4-formamidothiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Methyl 4-aminothiophene-3-carboxylate | HCID 2777610 | — |
| Reactant | Sodium Acetate Trihydrate | HCID 23665404 | — |
| Solvent | Water | HCID 962 | — |
| Product | Methyl 4-formamidothiophene-3-carboxylate | HCID 2777637 | — |
Reaction Steps
A stirred solution of methyl 4-amino-3-thenoate (4 g), sodium acetate trihydrate (2.8 g) and formic acid (27 ml) was heated at 95° C. for 1 hour. On cooling the solution was poured into water, and the solution filtered to give the title product as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432964B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-b19aee2082594237b630c37977f4c646 |
| Source note | uspto-grants-2002_08 |