Bromine → 53826-75-8

HRID 2303295Notes

Reaction equation

HRID 2303295 reaction equation
Br[C:2]1[S:3][C:4]([Br:12])=[C:5]2[C:10]=1[C:9](=[O:11])[NH:8][CH:7]=[N:6]2.BrBr>C(O)(=O)C>[Br:12][C:4]1[S:3][CH:2]=[C:10]2[C:9](=[O:11])[NH:8][CH:7]=[N:6][C:5]=12

Participants

4

Reactant 2

HCID 24408BromineHCID 135854400HCID 135854400, compound

Product 1

HCID 13585440153826-75-8

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of the product from Example 12 (0.9 g) and bromine (0.3 ml) in glacial acetic acid (100 ml) were heated at 100° C. for 2 hours. On cooling the solvent was removed and the residue was dried. The residue was recrystallised from acetic acid to give the title product, m.p. 226-229° C.

Workup

  1. temperatureOn cooling the solvent
  2. customwas removed
  3. customthe residue was dried
  4. customThe residue was recrystallised from acetic acid

Sources & evidence

ORD record
ord-8e00d609f350423d8533d2fd13a160bf
Source dataset
uspto-grants-2002_08
Patent number
US06432964B1

Reaction notes

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