Ethanol → HCID 18460839, compound

HRID 2303301Notes

Reaction equation

HRID 2303301 reaction equation
C(O[CH:4]=[C:5]([C:11](=O)[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=1)[C:6]([O:8][CH2:9][CH3:10])=[O:7])C.S(O)(O)(=O)=O.C[NH:28][C:29](=[NH:31])[SH:30].[CH2:32](O)C>[Na]>[CH3:32][S:30][C:29]1[N:31]=[C:11]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=2)[C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][N:28]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 69157946HCID 69157946, compoundHCID 178485225HCID 178485225, compound

Product 1

HCID 18460839HCID 18460839, compound

Reagents, catalysts & solvents 1

HCID 5360545SodiumSolvent

Procedure

In ethanol in which sodium had been dissolved, ethyl 3-ethoxy-2-[(3-methoxyphenyl)acetyl]acrylate and methylisothiourea sulfate were reacted under heat reflux to obtain ethyl 2-methylsulfanyl-4-(3-methoxybenzyl)pyrimidine-5-carboxylate (yellow oil).

Workup

  1. temperatureunder heat
  2. temperaturereflux

Sources & evidence

ORD record
ord-f0ff00cde5ae42df9cf646332e85de37
Source dataset
uspto-grants-2002_08
Patent number
US06432963B1

Reaction notes

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