HCID 69944824, compound → HCID 22958908, compound

HRID 2303328Notes

Reaction equation

HRID 2303328 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH:11]2[CH:12]([O:14][CH:15]3[CH2:20][CH2:19][CH2:18][CH2:17][O:16]3)[CH2:13][CH:7]1[CH2:8][C:9](=[CH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH2:10]2)=[O:5])[CH3:2]>[Pt]>[CH2:1]([O:3][C:4]([N:6]1[CH:11]2[CH:12]([O:14][CH:15]3[CH2:20][CH2:19][CH2:18][CH2:17][O:16]3)[CH2:13][CH:7]1[CH2:8][CH:9]([CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[CH2:10]2)=[O:5])[CH3:2]

Participants

3

Reactant 1

HCID 69944824HCID 69944824, compound

Product 1

HCID 22958908HCID 22958908, compound

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

Hydrogenation of the 3-benzylidene-6-(tetrahydro-pyran-2-yloxy)-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid ethyl ester similarly to the procedure described in Step 4 of Example 1 over 5% platinum on carbon gave 0.3 g of a resin.

Sources & evidence

ORD record
ord-66b6c33a14624e059c8a8dfd82140309
Source dataset
uspto-grants-2002_08
Patent number
US06432976B1

Reaction notes

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