2,5-Dimethylpiperazine, trans- → Hydrochloric Acid

HRID 2303351Notes

Reaction equation

HRID 2303351 reaction equation
[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)[CH:4]=1.[CH3:21][C@H:22]1[CH2:27][NH:26][C@H:25]([CH3:28])[CH2:24][NH:23]1>>[ClH:1].[ClH:1].[ClH:1].[ClH:1].[CH3:20][O:19][C:11]1[CH:10]=[C:9]([C:5]2[CH:4]=[C:3]([CH2:2][N:23]3[CH2:24][C@@H:25]([CH3:28])[N:26]([CH2:2][C:3]4[CH:8]=[CH:7][N:6]=[C:5]([C:9]5[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=5)[CH:4]=4)[CH2:27][C@@H:22]3[CH3:21])[CH:8]=[CH:7][N:6]=2)[CH:14]=[C:13]([O:15][CH3:16])[C:12]=1[O:17][CH3:18].[ClH:1]

Participants

4

Reactant 2

HCID 2206722,5-Dimethylpiperazine, trans-HCID 120192374-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine

Product 2

HCID 313Hydrochloric AcidHCID 69352623HCID 69352623, compound

Procedure

4-Chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (123 mg) and trans-2,5-dimethylpiperazine (23 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a hydrochloride.

Sources & evidence

ORD record
ord-097d4108f9a547499ae2660817dfa623
Source dataset
uspto-grants-2002_08
Patent number
US06432957B1

Reaction notes

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