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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303366Generated: November 1, 2026

4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine → Hydrochloric Acid

https://huagongshe.com/reaction/2303366

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
ReactantHCID 12019241HCID 12019241—
ProductHydrochloric AcidHCID 313—
ProductHCID 69351740HCID 69351740—

Reaction Steps

(3R)-3-Isopropyl-2-oxo-1-[[2-(3,4,5-trimethoxy-phenyl)pyridin-4-yl]methyl]piperazine (109 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (104 mg) were reacted in the same manner as in Example 4 to obtain the title compound as a hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432957B1
Source datasetuspto-grants-2002_08
ORD IDord-c36b7c8d98e04d4281e169c8e39fe97f
Source noteuspto-grants-2002_08