Potassium tert-butoxide → HCID 18461555, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 12 (4.0 g) in toluene was treated with potassium tert-butoxide (30 mL, 1 M in tert-butanol) under an inert atmosphere. After heating at 110° C. for 1 h, the mixture was cooled and the resulting precipitate was collected by filtration. The precipitate was washed with Et2O (3 times) giving 5 g of 3-hydroxy-6-methanesulfonyl-benzofuran-2-carbonitrile 13 as a yellow solid.

Provenance & Evidence