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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303620Generated: November 1, 2026

Hydrochloric Acid → HCID 18187862, compound

https://huagongshe.com/reaction/2303620

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 18187735HCID 18187735—
SolventMethanolHCID 887—
ProductHCID 18187862HCID 18187862—

Reaction Steps

A solution of 1-(t-butoxycarbonyl)-4-(3-(quinolin-3-yl)propyl)piperidine from Step A (240 mg, 0.68 mmol) in 1M HCl solution (8 mL) in methanol was stirred at rt for 48 h. The solution was concentrated and the residue crystallized from ethyl acetate to afford the title compound (182 mg),

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432981B1
Source datasetuspto-grants-2002_08
ORD IDord-44d94733aea946cd8f6141f524c11e29
Source noteuspto-grants-2002_08