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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303768Generated: November 1, 2026

HCID 18461431, compound → HCID 86758427, compound

https://huagongshe.com/reaction/2303768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18461431HCID 18461431—
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ProductHCID 86758427HCID 86758427—

Reaction Steps

A mixture of t-butyl N-{2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-[3-(morpholin-4-yl)phenoxy]phenyl)-N-methylcarbamate and 20 ml of 4N hydrochloric acid/dioxane was stirred at room temperature for 3 hours. The reaction mixture was evaporated to dryness under reduced pressure, followed by the addition of ether. The insoluble product was collected by filtration and washed with ether, whereby 1.27 g of the title compound were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-34650a43780042b390e542ad0fb04735
Source noteuspto-grants-2002_08