HCID 18461375, compound → HCID 86758435, compound

Participants

Reaction Steps

A mixture of t-butyl N-{2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-(4-hydroxy-2,3-dimethylphenoxy)phenyl}-N-methylcarbamate (2.35 g) and 4N hydrogen chloride/dioxane (20 ml) was stirred at ambient temperature for 44 hours. The solvent of the reaction mixture was evaporated to dryness. To the residue was added ethyl acetate and insoluble product was collected by filtration and washed with ethyl acetate to give the title compound (1.82 g).

Provenance & Evidence