1,4-Dioxane hydrochloride → HCID 178478924, compound

Participants

Reaction Steps

A mixture of t-butyl N-{2-[4-(2,4-dioxothiazolidine-5-ylmethyl)phenoxyacetylamino]-5-[4-(tetrazol-5-yl)phenoxy]phenyl}-N-methylcarbamate (0.76 g) and 4N hydrogen chloride/dioxane (20 ml) was stirred at ambient temperature for 24 hours. The solvent of the reaction mixture was evaporated. To the residue was added ethyl acetate and insoluble product was isolated by filtration and washed with ethyl acetate to give the title compound (0.44 g).

Provenance & Evidence