HCID 18461425, compound → HCID 18461459, compound

HRID 2303880Notes

Reaction equation

HRID 2303880 reaction equation
[CH3:1][N:2]([C:10]1[CH:15]=[C:14]([S:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=2)[CH:13]=[CH:12][C:11]=1[N+:23]([O-])=O)[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]>[Pd].CO>[NH2:23][C:11]1[CH:12]=[CH:13][C:14]([S:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=2)=[CH:15][C:10]=1[N:2]([CH3:1])[C:3](=[O:9])[O:4][C:5]([CH3:6])([CH3:7])[CH3:8]

Participants

4

Reactant 1

HCID 18461425HCID 18461425, compound

Product 1

HCID 18461459HCID 18461459, compoundYield 78.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

In a similar manner to that described in Reference Example 7, a reaction was carried out using t-butyl N-methyl-N-[2-nitro-5-(pyridine-2-ylthio)phenyl]carbamate (1.08 g), palladium on carbon (10%, 1.00 g) and methanol (20 ml) and the reaction mixture was purified to give the title compound (0.78 g).

Workup

  1. customthe reaction mixture was purified

Sources & evidence

ORD record
ord-b312bfcd63b84ccb9bd11e43bbcd1b18
Source dataset
uspto-grants-2002_08
Patent number
US06432993B1

Reaction notes

Loading…