HCID 131723435, compound → HCID 131723432, compound

HRID 2303903Notes

Reaction equation

HRID 2303903 reaction equation
[CH3:1][N:2]([C:10]1[CH:15]=[C:14]([S:16][C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)[CH:13]=[CH:12][C:11]=1[N+:24]([O-])=O)[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]>[Pd].CO>[NH2:24][C:11]1[CH:12]=[CH:13][C:14]([S:16][C:17]2[CH:18]=[CH:19][C:20]([CH3:23])=[CH:21][CH:22]=2)=[CH:15][C:10]=1[N:2]([CH3:1])[C:3](=[O:9])[O:4][C:5]([CH3:6])([CH3:8])[CH3:7]

Participants

4

Reactant 1

HCID 131723435HCID 131723435, compound

Product 1

HCID 131723432HCID 131723432, compoundYield 83.4%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

In a similar manner to that described in Reference Example 7, a reaction was carried out using t-butyl N-methyl-N-[5-(4-methylthiophenoxy)-2-nitrophenyl]carbamate (2.53 g), palladium on carbon (10%, 2.5 g) and methanol (55 ml) and the reaction mixture was purified to give the title compound (1.94 g).

Workup

  1. customthe reaction mixture was purified

Sources & evidence

ORD record
ord-2b0dfaa2d6e647729854c0f3f83df705
Source dataset
uspto-grants-2002_08
Patent number
US06432993B1

Reaction notes

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