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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303920Generated: November 1, 2026

HCID 18537656, compound → HCID 18537692, compound

https://huagongshe.com/reaction/2303920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18537656HCID 18537656—
ReactantToluene ethylacetateHCID 21584019—
CatalystPalladiumHCID 23938—
SolventEthyl acetate hexaneHCID 21226206—
ProductHCID 18537692HCID 18537692100.5%

Reaction Steps

In a similar manner to that described in Reference Example 7, a reaction was carried out using t-butyl N-{5-[4-(t-butoxycarbonyl-n-hexylamino)phenoxy]-2-nitrophenyl}-N-methylcarbamate (13.8 g), palladium on carbon (10%, 1.0 g) and toluene/ethyl acetate=1/1 (140 ml) and the reaction mixture was purified to give the title compound (13.1 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-b5ee701cd8fd409698e6883bcc8c06de
Source noteuspto-grants-2002_08