HRID2304273

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22665676

未命名化合物

结构：CC1CCN(C(=O)C(Cc2cc3c(N)nccc3s2)NS(=O)(=O)c2ccc(OC3CCOCC3)cc2)CC1

HCID22665795

未命名化合物

PRODUCTS

生成物

结构：COc1ccc2c(c1)CN(S(=O)(=O)NC(Cc1cc3c(N)nccc3s1)C(=O)N1CCC(C)CC1)CC2

HCID86756458

未命名化合物

PROCEDURE

实验过程

This compound was prepared from 200 mg of 7-methoxy-3,4-dihydro-1H-isoquinoline-2-sulfonyl chloride and 210 mg of 30a using the procedure described for 58c. Yield: 110 mg; m.p. 175-176° C., (+)-FAB-MS: 544 (MH+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d14e76e413a84542b44bf7da20147099
来源数据集: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06432955B1
来源说明: uspto-grants-2002_08

反应 SMILES

[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][N:9]([S:13](Cl)(=[O:15])=[O:14])[CH2:10]2)=[CH:5][CH:4]=1.[NH2:17][C:18]1[C:23]2[CH:24]=[C:25]([CH2:27][CH:28]([NH:38]S(C3C=CC(OC4CCOCC4)=CC=3)(=O)=O)[C:29]([N:31]3[CH2:36][CH2:35][CH:34]([CH3:37])[CH2:33][CH2:32]3)=[O:30])[S:26][C:22]=2[CH:21]=[CH:20][N:19]=1>>[NH2:17][C:18]1[C:23]2[CH:24]=[C:25]([CH2:27][CH:28]([NH:38][S:13]([N:9]3[CH2:8][CH2:7][C:6]4[C:11](=[CH:12][C:3]([O:2][CH3:1])=[CH:4][CH:5]=4)[CH2:10]3)(=[O:15])=[O:14])[C:29]([N:31]3[CH2:32][CH2:33][CH:34]([CH3:37])[CH2:35][CH2:36]3)=[O:30])[S:26][C:22]=2[CH:21]=[CH:20][N:19]=1