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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2304376Generated: October 31, 2026

Anisole → 4'-Methoxyacetophenone

https://huagongshe.com/reaction/2304376

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnisoleHCID 7519—
ReactantAcetic AnhydrideHCID 7918—
Product4'-MethoxyacetophenoneHCID 7476—

Reaction Steps

The reaction between anisole and acetic anhydride was performed in substantially the same manner as in Example 49, except that each of the compounds as synthesized in Examples 42 and 43 was individually used as the Lewis acid catalyst. The yields of the reaction product (i.e., p-methoxyacetophenone) are shown in Table 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06436866B1
Source datasetuspto-grants-2002_08
ORD IDord-99d38ccd5c814c2a99a634c7902ca636
Source noteuspto-grants-2002_08