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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2304478Generated: November 2, 2026

Isopropanol → (7s, 8r, 9r)-2,3-Dimethyl-8-hydroxy-9-phenyl-7-(2-propoxy)-7,8,9,10-tetrahydro-imidazo[1,2-h][1,7]-naphthyridine

https://huagongshe.com/reaction/2304478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropanolHCID 3776—
ReactantHCID 21873957HCID 21873957—
Product(7s, 8r, 9r)-2,3-Dimethyl-8-hydroxy-9-phenyl-7-(2-propoxy)-7,8,9,10-tetrahydro-imidazo[1,2-h][1,7]-naphthyridineHCID 66952632—

Reaction Steps

1 g of the title compound of melting point 168-9° C. is obtained by reaction of 3 g of 7R, 8R, 9R)-2,3-dimethyl-7,8-dihydroxy-9-phenyl-7,8,9,10-tetrahydro-imidazo[1,2-h][1,7]naphthyridine with 2-propanol according to Example 1, Method a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06436953B1
Source datasetuspto-grants-2002_08
ORD IDord-bfe2f5f7e83041bfb88b4cd287c8f79b
Source noteuspto-grants-2002_08