Hydrochloric Acid → HCID 18459292, compound

Participants

Reaction Steps

A solution of 2-hydroxy-2-[(4-methoxybenzenesulfonyl)methyl]-3-(N-benzenecarbonylamino)-propionic acid, ethyl ester (0.27 g) in 4 mL of methanol is stirred with 1 mL of 1N sodium hydroxide for 3 hours. The reaction mixture is acidified with 1N HCl and the solvent is removed under reduced pressure. The residue is triturated twice with warm ethyl acetate. The ethyl acetate is removed, affording the title compound as a white solid.

Provenance & Evidence