Diethyl Ether → HCID 54209658, compound

HRID 2305079Notes

Reaction equation

HRID 2305079 reaction equation
Cl.[C:2]([O:6][NH2:7])([CH3:5])([CH3:4])[CH3:3].[Cl:8][CH2:9][C:10](=O)[CH3:11].C(OCC)C>O>[C:2]([O:6][N:7]=[C:10]([CH2:9][Cl:8])[CH3:11])([CH3:5])([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 6571ChloroacetoneHCID 2777906O-tert-butylhydroxylamine hydrochloride

Product 1

HCID 54209658HCID 54209658, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 1.51 g of O-tert-butylhydroxylamine hydrochloride, 0.93 g of chloroacetone, and 10 ml of diethyl ether is stirred at room temperature for 3 hours, poured into water, and extracted twice with diethyl ether. The diethyl ether layers are combined, washed with water, dried over anhydrous magnesium sulfate, and concentrated, which affords chloroacetone O-tert-butyloxime.

Workup

  1. extractionextracted twice with diethyl ether
  2. washwashed with water
  3. dry with materialdried over anhydrous magnesium sulfate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-3b810c26081e4461a78439f116078579
Source dataset
uspto-grants-2002_08
Patent number
US06437184B1

Reaction notes

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