化工社化工社 化学情報印刷レポート · 研究参考用
1-Butanol → n-Butyl 3,5-dihydroxy-adamantanecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Butanol | HCID 263 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 3,5-Dihydroxyadamantane-1-carboxylic acid | HCID 12010647 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | n-Butyl 3,5-dihydroxy-adamantanecarboxylate | HCID 23435153 | — |
反応手順
A mixture of 300 mmole of the above-prepared 3,5-dihydroxy-1-adamantanecarboxylic acid, 450 mmole of n-butanol, 15 mmole of sulfuric acid, and 900 ml of toluene was stirred under reflux of toluene for 5 hours. The reaction mixture was concentrated and was then subjected to column chromatography on a silica gel to yield n-butyl 3,5-dihydroxy-adamantanecarboxylate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06440636B1 |
| 出典データセット | uspto-grants-2002_08 |
| ORD ID | ord-3129ac2fca624c0fb4f79995426da071 |
| 出典メモ | uspto-grants-2002_08 |