Methyl iodide → Hydrogen iodide

HRID 2305306Notes

Reaction equation

HRID 2305306 reaction equation
[CH:1](=[N:8][N:9]1[CH2:13][CH2:12][NH:11][C:10]1=[S:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][I:16]>CO>[CH:1](=[N:8][N:9]1[CH2:13][CH2:12][N:11]=[C:10]1[S:14][CH3:15])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[IH:16]

Participants

5

Reactant 2

HCID 6328Methyl iodideHCID 73840649HCID 73840649, compound

Product 2

HCID 24841Hydrogen iodideHCID 54448851HCID 54448851, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5 g of 1-benzylideneamino-imidazolidine-2-thion are suspended in 40 ml of methanol and treated with 1.7 ml of methyliodide. The mixture obtained is refluxed for ca. one hour and the solvent is evaporated off. 1-Benzylideneamino-2-methylthio-4,5-dihydro-1H-imidazole in the form of a hydroiodide is obtained in solid form, to which 120 ml of water and 70 ml of an anion exchange resin in chloride form (Amberlite IRA-400 (Cl)R) are added. The mixture is stirred for ca. 2 hours at room temperature, filtrated and lyophilized. 1-Benzylideneamino-2-methylthio-4,5-dihydro-1H-imidazole in the form of a hydrochloride is obtained in the form of a lyophilisate.

Workup

  1. customThe mixture obtained
  2. temperatureis refluxed for ca. one hour
  3. customthe solvent is evaporated off

Sources & evidence

ORD record
ord-b515248b040f428f877b420dff66edaf
Source dataset
uspto-grants-2002_08
Patent number
US06440957B1

Reaction notes

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