Ammonia → Hydrochloric Acid

HRID 2305307Notes

Reaction equation

HRID 2305307 reaction equation
[CH:1](=[N:8][N:9]1[CH2:13][CH2:12][N:11]=[C:10]1SC)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:16].N.C(#[N:20])C>CO>[NH2:20][C:10]1[N:9]([N:8]=[CH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH2:13][CH2:12][N:11]=1.[ClH:16]

Participants

7

Reactant 4

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 6342AcetonitrileHCID 54448851HCID 54448851, compound

Product 2

HCID 313Hydrochloric AcidHCID 53815935HCID 53815935, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1 g of 1-benzylideneamino-2-methylthio-2-imidazoline in the form of a hydrochloride in 10 ml of methanol are treated with 0.33 ml of NH3 (28% in H2O). The mixture obtained is refluxed for ca. 5 hours and a precipitate obtained is filtrated off. From the filtrate obtained the solvent is evaporated off. The residue obtained is treated with acetonitrile. The precipitate obtained is filtrated off and dried. Solid 2-amino-1-benzylideneamino-4,5-dihydro-1H-imidazole in the form of a hydrochloride is obtained.

Workup

  1. customThe mixture obtained
  2. temperatureis refluxed for ca. 5 hours
  3. customa precipitate obtained
  4. filtrationis filtrated off
  5. customFrom the filtrate obtained the solvent
  6. customis evaporated off
  7. customThe residue obtained
  8. customThe precipitate obtained
  9. filtrationis filtrated off
  10. customdried

Sources & evidence

ORD record
ord-d814395f42e94cd38e4e7385ba571813
Source dataset
uspto-grants-2002_08
Patent number
US06440957B1

Reaction notes

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