Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 5-[2-(Trifluoromethyl)phenyl]furfural | HCID 688280 | — |
| Reactant | HCID 178516656 | HCID 178516656 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 9863961 | HCID 9863961 | 55.7% |
Reaction Steps
A suspension of 0.242 g (1 mmol) of 5-(2-trifluoromethylphenyl)furfural, 0.144 g (1 mmol) of 4,6-dihydroxy-2-mercaptopyrimidine, and a drop of piperidine in 6 ml of ethanol was stirred with heating at 80° C. for 4 hours. Upon cooling, the orange suspension was poured into 50 ml of water and sonicated for 10 minutes. Filtration of the orange solvent and drying provided 0.204 g of the product as an orange powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06440985B1 |
|---|
| Source dataset | uspto-grants-2002_08 |
|---|
| ORD ID | ord-5f156160d9b741af8bc023ca346c1a87 |
|---|
| Source note | uspto-grants-2002_08 |
|---|
