3-Amino-1,2-propanediol → HCID 9841292, compound

HRID 2305487Notes

Reaction equation

HRID 2305487 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([N:12]2[CH2:21][CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH:3]=1.[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][OH:26]>>[CH2:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:20][CH2:21][N:12]1[C:4]1[CH:3]=[C:2]([NH:22][CH2:23][CH:24]([OH:27])[CH2:25][OH:26])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18433086HCID 18433086, compound

Product 1

HCID 9841292HCID 9841292, compound

Procedure

The title compound, MS: m/e=349 (M+), was prepared from 4-chloro-2-(3,4-dihydro-1H-isoquinolin-2-yl)-quinoline and (RS)-3-amino-1,2-propanediol.

Sources & evidence

ORD record
ord-7e0fc2492bbe47dfa5a5615dbd0b9c2e
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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