3-Amino-1,2-propanediol → HCID 18433070, compound

HRID 2305495Notes

Reaction equation

HRID 2305495 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([Cl:19])[CH:13]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[Cl:19][C:14]1[CH:13]=[C:12]([C:4]2[CH:3]=[C:2]([NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:17]=[CH:16][C:15]=1[CH3:18]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18433102HCID 18433102, compound

Product 1

HCID 18433070HCID 18433070, compound

Procedure

The title compound, m.p. 230-231° C. and MS: m/e=343.1 (M+H+), was prepared from 4-chloro-2-(3-chloro-4-methyl-phenyl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-c377d4f7ea714d798a6b0e200dfef562
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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