3-Amino-1,2-propanediol → HCID 18432990, compound

HRID 2305496Notes

Reaction equation

HRID 2305496 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([C:4]2[CH:3]=[C:2]([NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 15481382HCID 15481382, compound

Product 1

HCID 18432990HCID 18432990, compound

Procedure

The title compound, m.p. 216-218° C. and MS: m/e=324 (M+), was prepared from 4-chloro-2-(4-methoxy-phenyl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-e2a3d796556a41d4b684ed9852630fd4
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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