3-Amino-1,2-propanediol → HCID 18433018, compound

HRID 2305500Notes

Reaction equation

HRID 2305500 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([CH3:19])[CH:13]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[CH3:19][C:14]1[CH:13]=[C:12]([C:4]2[CH:3]=[C:2]([NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:17]=[CH:16][C:15]=1[CH3:18]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 16096279HCID 16096279, compound

Product 1

HCID 18433018HCID 18433018, compound

Procedure

The title compound, m.p. 248° C. and MS: m/e=322 (M+), was prepared 4-chloro-2-(3,4-dimethyl-phenyl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-e30ec7e4f09344b5a9fb30b89b7e00cc
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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