3-Amino-1,2-propanediol → HCID 18433089, compound

HRID 2305501Notes

Reaction equation

HRID 2305501 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)[CH:3]=1.[NH2:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23]>>[ClH:1].[C:15]1([CH3:18])[CH:16]=[CH:17][C:12]([C:4]2[CH:3]=[C:2]([NH:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 11118595HCID 11118595, compound

Product 1

HCID 18433089HCID 18433089, compound

Procedure

The title compound, m.p. 255-257° C. and MS: m/e=308 (M+), was prepared from 4-chloro-2-p-tolyl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-bbb69b2f2aa94e4b941ef1da15b0e5b5
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

Loading…