3-Amino-1,2-propanediol → HCID 18433126, compound

HRID 2305506Notes

Reaction equation

HRID 2305506 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[CH3:13][O:12][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24])=[CH:3][C:4]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[N:5]2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 107544774-Chloro-7-methoxy-2-phenylquinoline

Product 1

HCID 18433126HCID 18433126, compound

Procedure

The title compound, m.p. 218-222° C., and MS: m/e=325.3 (M+H+), was prepared from 4-chloro-7-methoxy-2-phenyl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-630441320745427a82da923c391f9c8f
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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