3-Amino-1,2-propanediol → HCID 18432950, compound

HRID 2305507Notes

Reaction equation

HRID 2305507 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[C:14]([Cl:19])[CH:13]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[Cl:19][C:14]1[CH:13]=[C:12]([C:4]2[CH:3]=[C:2]([NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:17]=[CH:16][C:15]=1[Cl:18]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18432955HCID 18432955, compound

Product 1

HCID 18432950HCID 18432950, compound

Procedure

The title compound, m.p. 234-236° C., and MS: m/e=362 (M+), was prepared from 4-chloro-2-(3,4-dichloro-phenyl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-8fc1c86018474e68806280a7e3151384
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

Loading…