3-Amino-1,2-propanediol → HCID 18433009, compound

HRID 2305509Notes

Reaction equation

HRID 2305509 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([Cl:20])[CH:13]=2)[CH:3]=1.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25]>>[ClH:1].[Cl:20][C:14]1[CH:13]=[C:12]([C:4]2[CH:3]=[C:2]([NH:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:17]=[CH:16][C:15]=1[O:18][CH3:19]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18432969HCID 18432969, compound

Product 1

HCID 18433009HCID 18433009, compound

Procedure

The title compound, m.p. 205-210° C., and MS: m/e=358 (M+), was prepared from 4-chloro-2-(3-chloro-4-methoxy-phenyl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-7d382da451f64f25b48fc274fb556fab
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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