3-Amino-1,2-propanediol → HCID 18433013, compound

HRID 2305519Notes

Reaction equation

HRID 2305519 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:13]=[C:14]3[C:18](=[CH:19][CH:20]=2)[CH2:17][CH2:16][CH2:15]3)[CH:3]=1.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25]>>[ClH:1].[CH2:17]1[C:18]2[C:14](=[CH:13][C:12]([C:4]3[CH:3]=[C:2]([NH:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])[C:11]4[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=4)[N:5]=3)=[CH:20][CH:19]=2)[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 184329944-Chloro-2-(2,3-dihydro-1H-inden-5-yl)quinoline

Product 1

HCID 18433013HCID 18433013, compound

Procedure

The title compound, m.p. 157-160° C., MS: m/e=334 (M+), was prepared from 4-chloro-2-indan-5-yl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-6d4ef847dca94a938513b5ddc84caace
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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