3-Amino-1,2-propanediol → HCID 18433036, compound

HRID 2305524Notes

Reaction equation

HRID 2305524 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([N:12]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH:3]=1.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25]>>[ClH:1].[CH2:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:20][N:12]1[C:4]1[CH:3]=[C:2]([NH:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18433077HCID 18433077, compound

Product 1

HCID 18433036HCID 18433036, compound

Procedure

The title compound, m.p. 295-301° C., and MS: m/e=336.2 (M+H+), was prepared from 4-chloro-2-(1,3-dihydro-isoindol-2-yl)-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-27af0914b3de44078425eb4e565a6d5d
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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