3-Amino-1,2-propanediol → HCID 18433098, compound

HRID 2305528Notes

Reaction equation

HRID 2305528 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]>>[ClH:1].[CH3:13][O:12][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:6]=1[N:5]=[C:4]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH:3]=[C:2]2[NH:20][CH2:21][CH:22]([OH:25])[CH2:23][OH:24]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 144377554-Chloro-8-methoxy-2-phenylquinoline

Product 1

HCID 18433098HCID 18433098, compound

Procedure

The title compound, m.p. 110-116° C., and MS: m/e=325.3 (M+H+), was prepared from 4-chloro-8-methoxy-2-phenyl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-de0795c343954eb59d52f937053212bb
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

Loading…