3-Amino-1,2-propanediol → HCID 136331673, compound

HRID 2305529Notes

Reaction equation

HRID 2305529 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([OH:12])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]=1.[NH2:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23]>>[ClH:1].[OH:12][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([NH:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23])=[CH:3][C:4]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:5]2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 136331671HCID 136331671, compound

Product 1

HCID 136331673HCID 136331673, compound

Procedure

The title compound, m.p. 267-268° C., and MS: m/e=310 (M+), was prepared from 4-chloro-2-phenyl-quinolin-7-ol and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-511b3eadb4664c73a3d29f6889292f51
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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