3-Amino-1,2-propanediol → HCID 18432936, compound

HRID 2305530Notes

Reaction equation

HRID 2305530 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:13]=[C:14]([CH3:18])[CH:15]=[CH:16][CH:17]=2)[CH:3]=1.[NH2:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23]>>[ClH:1].[C:14]1([CH3:18])[CH:15]=[CH:16][CH:17]=[C:12]([C:4]2[CH:3]=[C:2]([NH:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:13]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 11139662HCID 11139662, compound

Product 1

HCID 18432936HCID 18432936, compound

Procedure

The title compound, m.p. 208-215° C., and MS: m/e=309.2 (M+H+), was prepared from 4-chloro-2-m-tolyl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-965939e08ef1481885cd0ef6da9d478a
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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